Cannabidivarin (CBDV) is a psychoactive, non-psychotropic decarboxylated propyl analogue phytocannabinoid of CBD found in heated cannabis. It was discovered in 1964 as a homologue to CBD, and is not a CB1 agonist but appears to activate and desensitize the vanilloid TRPV1. Preliminary research suggests CBDV is what helps differentiate strains bred specifically for treating seizure disorders, and it is currently undergoing research to see its effects in those with autism.
How CBDV Assists
CBDV in particular has been shown to assist with asthma, bacterial infections, bronchitis, inflammatory bowel disease, irritable bowel syndrome, Crohn’s disease, ulcerative colitis, seizures, epilepsy, spasticity, nausea, skin disorders, acne, dermatitis, psoriasis and eczema.
- Ross, SA. ElSohly, MA. Sultana, GN. Mehmedic, Z. Hossain, CF. Chandra, S. Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. Phytochemical Analysis. (2005)
- Iannotti, FA. Hill, CL. Leo, A. Alhusaini, A. Soubrane, C. Mazzarella, E. Russo, EB. Whalley, BJ. Di Marzo, V. Stephens, GJ. Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability. ACS Chemical Neuroscience. (2014)
- Miller, S. Understanding Cannabinoids – CBC, CBG, THCV, and CBDV. Green Flower. (2018)