What Is CBG
Cannabigerol (CBG) is the decarboxylated phytocannabinoid of CBGa found in heated cannabis. It is a psychoactive, non-psychotropic “stem cell” phytocannabinoid, and alongside its precursor CBGa was discovered in 1964. During cannabis’ growth, the majority of CBG is converted into other phytocannabinoids, and most strains rarely have any more than 1% of its phytocannabinoids left as CBG. Typically, cannabis high in CBG is an indication of an immature plant. CBG acts on both CB1 and CB2 receptors, though it affects them much less than THC, and has been shown to react with 5-HT1a receptors as well. Perhaps most shockingly, CBG has been contending with THC as the most effective cancer-killer, showing its effectiveness against colon cancer, breast cancer, prostate and stomach cancer, and even a cell line of oral cancer.
CBG in particular has been shown to assist with anxiety, OCD, stress, bacterial infections, cancer, depression, glaucoma, anorexia, cachexia, bulimia, Huntington’s disease, skin disorders, acne, dermatitis, psoriasis and eczema.
Citations
- Ross, SA. ElSohly, MA. Sultana, GN. Mehmedic, Z. Hossain, CF. Chandra, S. Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. Phytochemical Analysis. (2005)
- Cascio, MG. Gauson, LA. Stevenson, LA. Ross, RA. Pertwee, RG. Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. British Journal of Pharmacology. (2010)
- Valdeolivas, S. Navarrete, C. Cantarero, I. Bellido, ML. Munoz, E. Sagredo, O. Neuroprotective properties of cannabigerol in Huntington’s disease: studies in R6/2 mice and 3-nitropropionate-lesioned mice. Neurotherapeutics. (2015)
- What is CBG (Cannabigerol)? Leaf Science. (2017)
- Miller, S. Understanding Cannabinoids – CBC, CBG, THCV, and CBDV. Green Flower. (2018)