Though widely regarded as unique to cannabis, there are a few other plants capable of producing their own phytocannabinoids that likewise interact with our endocannabinoid system. Many of these chemicals are technically lipophilic alkamides, but their interactions with cannabinoid receptors make them qualify as phytocannabinoids themselves. Hops Most surprisingly, a species of hops known as […]
Though detected in cannabis, dozens of phytocannabinoids have not yet been studied for their effects or interactions in the endocannabinoid system. These include cannabichromenenic acid (CBCa), cannabichromanone (CBCN), cannabichromevarin (CBCV) a propyl analogue of CBC, cannabinodiol (CBDL), cannabidivarinic acid (CBDVa) a propyl analogue of CBDa, cannabielsoin (CBE) an artifact derived from CBD, cannabigerol monomethyl ether […]
Cannabinol (CBN) is a nonenzymatic breakdown product of THC and THCV exposed to UV light and oxygen, and is commonly found in aged cannabis. Discovered in 1940 by Roger Adams, it is a partially psychotropic, psychoactive phytocannabinoid typically used as an indicator of how fresh a dried bud is, but is also known to be […]
Cannabichromene (CBC) is a psychoactive non-psychotropic phytocannabinoid. It was discovered in 1964 and is the decarboxylated form of CBCa found in heated juvenile cannabis. As the plant matures, the CBC levels lower, but GW Pharmaceutical was able to develop a mutated Cannabis sativa variety that has difficulties producing THC and CBD, allowing the CBC to […]
Cannabidivarin (CBDV) is a psychoactive, non-psychotropic decarboxylated propyl analogue phytocannabinoid of CBD found in heated cannabis. It was discovered in 1964 as a homologue to CBD, and is not a CB1 agonist but appears to activate and desensitize the vanilloid TRPV1. Preliminary research suggests CBDV is what helps differentiate strains bred specifically for treating seizure […]
Cannabidiol (CBD) is the decarboxylated phytocannabinoid of CBDa found in heated cannabis. It was discovered in 1940 by Roger Adams and is the second most abundant phytocannabinoid found in cannabis. Because it mostly affects CB2 receptors instead of CB1, it produces no psychotropic effects, and its medicinal uses can be felt immediately. Any strain containing […]
Cannabidiolic acid (CBDa) is a psychoactive, non-psychotropic acidic precursor to CBD found in raw cannabis. CBDa predominantly binds to CB2 receptors, but like CBD, can interact with 5-HT1a serotonin receptors as well. Long-term use of CBDa has shown it to provide subtle relief of varying symptoms over time, between 3 days and 4 weeks. How […]
Tetrahydrocannabivarin (THCV) is the decarboxylated propyl analogue phytocannabinoid of THCVa found in heated cannabis, and a homologue to THC. It was discovered in 1964 and is a high-energy and relatively abundant psychoactive non-psychotropic phytocannabinoid. It seems to mimic CBD’s anxiety relief, and recent research has shown it to be fairly effective in appetite-suppression, lending to […]
What is THC Tetrahydrocannabinol (THC) is the decarboxylated phytocannabinoid of THCa and a precursor to CBN found in heated cannabis. It is the dominant psychoactive, psychotropic phytocannabinoid in cannabis, and was discovered in 1940 by Roger Adams. It’s the reason we feel euphoric, happy and hungry after consumption. Today, most cannabis strains have a THC […]
What is THCa Tetrahydrocannabinolic acid (THCa) is a psychoactive, non-psychotropic acidic precursor to THC, CBNa and CBN found in raw cannabis. THCa doesn’t appear to interact with either CB1 or CB2 receptors, and research is sparse in terms of its effects. Raw cannabis leaves are popularly juiced or brewed into teas for their THCa content. […]
