What is THC
Tetrahydrocannabinol (THC) is the decarboxylated phytocannabinoid of THCa and a precursor to CBN found in heated cannabis. It is the dominant psychoactive, psychotropic phytocannabinoid in cannabis, and was discovered in 1940 by Roger Adams. It’s the reason we feel euphoric, happy and hungry after consumption. Today, most cannabis strains have a THC content of around 12% to 20%, with anything above 20% being considered “premium.” Δ9-THC (Δ1-THC) is the most common homologue of THC. Much more rare, Δ8-THC (Δ6-THC) is present only in trace amounts or as an artifact of laboratory analysis, and is less psychotropically potent than Δ9-THC, typically described as producing a more sedative feeling than mental stimulation. Both can also exist as either the much more common low-rotating (LR) THC, or the much rare high-rotating (HR) THC, typically only achievable through a complicated isomerization process.
THC in particular has been shown to assist with ADHD, ADD, hyperactivity, Alzheimer’s disease, dementia, anorexia, cachexia, bulimia, anxiety, OCD, stress, atherosclerosis, arthritis, asthma, autism, bacterial infections, bronchitis, cancer, glaucoma, heart disease, inflammatory bowel disease, irritable bowel syndrome, Crohn’s disease, ulcerative colitis, insomnia, sleep apnea, liver disease, hepatitis, hemochromatosis, cirrhosis of the liver, low libido, lupus, migraine, multiple sclerosis, nausea, obesity, pain relief, seizures, epilepsy, spasticity, stroke and tourette’s syndrome.
THC is the only phytocannabinoid to commonly display short-term negative side effects, as it’s one of the few psychotropic phytocannabinoids. These side effects will fade over the course of a few hours, and typically not last longer than an hour or two after the high has faded. Common side effects include tachycardia, an increase in heart rate, minor anxiety and paranoia, dry mouth, bloodshot eyes, forgetfulness, dizziness, and potentially hallucinations if the dosage is severe. Different strains and consumption methods will produce different side effects of differing severity and length, but the average consumer considers most of these benign. The marijuana high is different for everyone, however, and not everyone enjoys the experience.
- Gough, TA. Taylor, BJ. Baker, PB. The tetrahydrocannabinol and tetrahydrocannabinolic acid content of cannabis products. The Journal of Pharmacy and Pharmacology. (1981)
- Ross, SA. ElSohly, MA. Sultana, GN. Mehmedic, Z. Hossain, CF. Chandra, S. Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. Phytochemical Analysis. (2005)
- Moldzio, R. Pacher, T. Krewenka, C. Kranner, B. Novak, J. Duvigneau, JC. Rausch, WD. Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP+ affected murine mesencephalic cultures. Phytomedicine. (2012)
- Piomelli, D. Russo, EB. The Cannabis sativa Versus Cannabis indica Debate: An Interview with Ethan Russo, MD. Cannabis and Cannabinoid Research. (2016)
- Miller, S. Understanding Cannabinoids – THCa and THC. Green Flower. (2018)
- Wilhelm, J. What Is Delta-8-THC and How Is It Different from Delta-9? Leafly. (2018)