Tetrahydrocannabivarin (THCV) is the decarboxylated propyl analogue phytocannabinoid of THCVa found in heated cannabis, and a homologue to THC. It was discovered in 1964 and is a high-energy and relatively abundant psychoactive non-psychotropic phytocannabinoid. It seems to mimic CBD’s anxiety relief, and recent research has shown it to be fairly effective in appetite-suppression, lending to its joke name of “diet weed.” THCV has also been shown to lessen a THC high, as it acts as a CB1 agonist at small doses, inhibiting the receptors and preventing more THC from being bound. It’s also been shown to partially bind to 5-HT1a receptors in the serotonin system, similar to CBD, and contributing to its antipsychotic effects.
THCV in particular has been shown to assist with anxiety, OCD, stress, ALS, Lou Gehrig’s disease, asthma, Alzheimer’s disease, dementia, schizophrenia, seizures, epilepsy, spasticity, bronchitis, diabetes, inflammatory bowel disease, irritable bowel syndrome, Crohn’s disease, ulcerative colitis, nausea, Parkinson’s disease, skin disorders, acne, dermatitis, psoriasis, eczema, osteoporosis, liver disease, hepatitis, hemochromatosis, cirrhosis of the liver, PTSD and obesity.
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